INJURED defender Jacob Weitering will miss Carlton's clash with Greater Western Sydney at Etihad Stadium on Sunday.

The in-form 20-year-old was initially named at half-back in the Blues' extended squad on Thursday evening, but hasn't recovered from a corked quad suffered in Carlton's victory over Gold Coast last week.

Cam O'Shea comes in as his replacement as the Blues' only change. Nick Graham, Patrick Kerr, Levi Casboult and Sam Kerridge have been named as the emergencies.

The Blues will be looking for a repeat of last year's thrilling one-point victory over the Giants, who have won seven of their past eight matches.

GWS has made three changes, bringing in Jeremy Cameron, Matt de Boer and debutant Aiden Bonar at the expense of injured trio Dylan Shiel, Tim Taranto and Sam Reid.

Carlton's Round 20 line-up:

Backs22. Caleb Marchbank17. Sam Rowe39. Dale Thomas
Half-backs13. Jed Lamb38. Ciaran Byrne6. Kade Simpson
Centreline4. Lochie O'Brien9. Patrick Cripps33. Jarrod Pickett
Half-forwards16. Darcy Lang30. Charlie Curnow5. Sam Petrevski-Seton
Forwards2. Paddy Dow7. Matthew Kennedy46. Matthew Wright
Followers10. Harry McKay3. Marc Murphy35. Ed Curnow
Interchange1. Jack Silvagni24. Cameron O'Shea27. Matthew Lobbe
29. Cameron Polson
Emergencies11. Sam Kerridge36. Patrick Kerr32. Nick Graham
41. Levi Casboult

In: O'Shea

Out: Weitering (quad)